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Unilateral Thoracic Soft-Tissue Accumulation of Bone Agent in Lung Cancer

Division of Nuclear Medicine, Department of Radiation Therapy and Nuclear Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

Correspondence: For reprints contact: Chan H. Park, MD, Div. of Nuclear Medicine, Thomas Jefferson University Hospital, 11th and Walnut Sts., Philadelphia, PA 19107.

ABSTRACT

One hundred thirty patients with lung cancer were studied to determine the incidence of unilateral thoracic soft-tissue accumulation (UTS) of ^99mTc methylene diphosphonate (MDP). The finding was present in 60 of 130 (46%) of the patients. Of 52 patients who had received radiation therapy to the primary tumor in the chest, 46 (88%) had UTS, while six (12%) did not. Radiation therapy to lung tumors was the most significant of the factors studied in unilateral soft-tissue uptake of bone agent in the thorax of patients with lung cancer.