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Radiophosphate Visualization of the Foreign Body Reaction to Wear Debris from Total Knee Prosthesis

Division of Nuclear Medicine, The Montreal General Hospital, Montreal, Quebec, Canada

Correspondence: For reprints contact: Leonard Rosenthall, MD, Division of Nuclear Medicine, The Montreal General Hospital, 1650 Cedar Ave., Montreal, Quebec, Canada H3G 1A4.

ABSTRACT

Three patients with total knee arthroplasties, in which the tibial and patellar articulating surfaces consisted of a polyethylene-carbon fiber composite, demonstrated technetium-99m methylene diphosphonate (MDP) deposition in the intraarticular space, whereas, the gallium-67 citrate images were normal. This was shown to be due to a synovial giant cell foreign body reaction to paniculate carbon fiber debris in one patient who required surgical revision of the prosthesis.