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Treatment of Axial Data in Three-Dimensional PET

Hospital of the University of Pennsylvania, Department of Radiology, Nuclear Medicine Section, Philadelphia, Pennsylvania

Correspondence: For reprints contact: Margaret E. Daube-Witherspoon, PhD, Nuclear Medicine Department, Clinical Center, Building 10, National Institutes of Health, Bethesda, MD 20892.

ABSTRACT

Improved axial spatial resolution in positron emission tomography (PET) scanners will lead to reduced sensitivity unless the axial acceptance angle for the coincidences is kept constant. A large acceptance angle, however, violates assumptions made in most reconstruction algorithms, which reconstruct parallel independent slices, rather than a three-dimensional volume. Two methods of treating the axial information from a volume PET scanner are presented. Qualitative and quantitative errors introduced by the approximations are examined for simulated objects with sharp boundaries and for a more anatomically realistic distribution with smooth activity gradients.

FOOTNOTES

^* Present address: The National Institutes of Health, Bethesda, MD.

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