HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Homma, S. Articles by Boucher, C. A. Search for Related Content PubMed PubMed Citation Articles by Homma, S. Articles by Boucher, C. A.

Correlates of Lung/Heart Ratio of Thallium-201 in Coronary Artery Disease

Cardiac Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
Division of Cardiology, Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia

Correspondence: For reprints contact: Sanjiv Kaul, MD, Div. of Cardiology, Box 158, University of Virginia School of Medicine, Charlottesville, VA 22908.

ABSTRACT

We studied 306 patients with chest pain (262 with coronary artery disease and 44 with no coronary artery disease) to determine which of 23 clinical, exercise, thallium, and angiographic variables best discriminate between patients with increased lung/heart ratios of thallium versus those with normal ratios. Normal lung/heart ratio values were defined using an additional 45 subjects with <1% probability of coronary artery disease. The number of diseased vessels was the best discriminator between patients with increased ratios versus those with normal ratios. Double product at peak exercise, number of segments with abnormal wall motion, patient gender, and duration of exercise were also significant discriminators. Using discriminant function analysis these variables could correctly identify 81% of cases with increased lung/heart ratios and 72% of cases with normal ratios. These results indicate that an increased lung/heart ratio of thallium reflects exercise-induced left ventricular dysfunction and affords a better understanding of why this thallium parameter is a powerful prognostic indicator in patients with chest pain.

FOOTNOTES

These data were presented in part at the 58th Annual Scientific Session of the American Heart Association in November 1985 in Washington, D.C.

This article has been cited by other articles:

				C. L. Papadopoulos, A. S. Doumas, G. Koliakos, C. Gitsios, and G. Sakadamis Increased Lung Uptake During Myocardial Scintigraphy Improves the Detection and Localization of Coronary Artery Disease Angiology, November 1, 1995; 46(11): 1015 - 1020. [Abstract] [PDF]