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Iodine-131 Treatment of Thyroid Cancer: Absorbed Dose Calculated from Post-Therapy Scans

Division of Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, Michigan

Correspondence: For reprints contact: Kenneth F. Koral, PhD, Div. of Nuclear Medicine, University of Michigan, R3054 Kresge II, Ann Arbor, MI 48109.

ABSTRACT

The radiation absorbed dose for nine neck lesions distributed among four thyroid-cancer patients was measured directly from images taken after administration of a treatment dose of ¹³¹I. The tumor volume was measured with anterior plus lateral pinhole images by determining magnification and assuming an ellipsoidal shape. Uptake and effective half-life were determined from serial anterior images by use of a calibration curve. Dose lower limits ranged from 2,400 to 29,900 rad. Response to treatment was judged on the basis of one or more follow-up scans at least 8 mo later. All lesions responded to the therapy administration which ranged from 150 to 175 mCi.

FOOTNOTES

^* Present address: Department of Radiology, University of Michigan Medical Center, Ann Arbor, MI.

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