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Lymphoscintigraphy in Lymphedema: An Aid to Microsurgery

Mayo Clinic and Mayo Foundation, Rochester, Minnesota

Correspondence: For reprints contact: Heinz W. Wahner, MD, Mayo Clinic, 200 First St. SW, Rochester, MN 55905.

ABSTRACT

The role of lymphoscintigraphy, performed with ^99mTc-labeled antimony sulfur colloid, in the diagnosis of lymphedema and as a test for selection of patients for microvascular operation was evaluated in 32 patients with primary and secondary lymphedema and four patients with other causes of leg edema. Lymphoscintigraphy clearly demonstrated if edema was of lymphatic origin. Five different image patterns were identified; abnormal image patterns could not be predicted from clinical history or physical findings. Quantitative evaluation of removal of the radioactive colloid from the injection site and appearance in lymph node sites and liver was of limited usefulness. Nine patients underwent various surgical procedures before or after lymphoscintigraphy. Lympho-venous anastomoses were possible only in patients who had patent lymph channels visible on lymphoscintigrams. Based on initial experience, lymphoscintigraphy seems to be useful to select patients for microvascular operation.

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