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Gated Xenon Scans for Right Ventricular Function

Departments of Medical Cardiology and Cardiac Surgery, Royal Infirmary, Glasgow, Scotland

Correspondence: For reprints contact: William Martin, PhD, Dept. of Medical Cardiology, Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER, Scotland.

ABSTRACT

The complex geometry of the right ventricle makes the use of radionuclides an attractive method for assessing right ventricular function. The use of the gated ¹³³Xe technique for this purpose offers several advantages. A short i.v. infusion over 20 sec of ¹³³Xe permits scans to be obtained, gated to the electrocardiogram at rest and during maximal exercise using a standard gamma camera. The method is both reproducible (3.5%) and repeatable (2.8%), and because of the short half-life within the patient with most of the radioisotope being excreted by the lungs, scans may be repeated within a few minutes and the radiation dose to the patient is small. Right ventricular ejection fraction obtained from gated xenon scans is shown to correlate well with measurements obtained from both standard gated technetium scans and first-pass studies.