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Opportunistic Intracranial Infection in AIDS Detection by Technetium-99m DTPA Brain Scintigraphy

Nuclear Medicine Service, Veterans Administration Medical Center
University of Kentucky Medical Center, Lexington, Kentucky

Correspondence: For reprints contact: Wei-Jen Shih, MD, Nuclear Medicine Service, University of Kentucky Medical Center, Lexington, KY 40536.

ABSTRACT

Radionuclide brain scintigraphy and computed tomography (CT) demonstrated cerebral lesions in two patients with acquired immunodeficiency disease syndrome (AIDS) complicated by opportunistic infection of the brain. In the detection of these cerebral lesions, [^99mTc]DTPA radionuclide scintigraphy was as reliable as CT. Since malignant lymphoma involving the brain has been seen with increasing frequency in patients with AIDS, the positive brain scan alone is nonspecific and should be correlated appropriately with the clinical setting.

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				M. Lorberboym, Y. Lampl, and M. Sadeh Correlation of 99mTc-DTPA SPECT of the Blood-Brain Barrier with Neurologic Outcome After Acute Stroke J. Nucl. Med., December 1, 2003; 44(12): 1898 - 1904. [Abstract] [Full Text] [PDF]