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Resolution of Massive Technetium-99m Methylene Diphosphonate Uptake in the Stomach in Vitamin D Intoxication

Departments of Nuclear Medicine and Internal Medicine, St. Radboud University Hospital, Nijmegen, The Netherlands

Correspondence: For reprints contact: Frans Corstens, MD, Dept., of Nuclear Medicine, St. Radboud University Hospital, Box 9101, 6500 HB Nijmegen, The Netherlands.

ABSTRACT

Vitamin D intoxication, which may result from zealous intake of health food supplements, may cause metastatic calcification. This is the first reported case of a patient with vitamin D intoxication who had massive gastric uptake of [^99mTc]MDP, but no lung uptake, with histologic documentation of the metastalic calcification by gastric biopsy. It is probable that the metastalic calcification was a highly metabolic process in this patient since the gastric uptake resolved within 3 wk when serum calcium and phosphate had returned to normal.