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Iodine-131 Metaiodobenzylguanidine Scintigraphy of Carcinoid Tumors

Departments of Medicine and Radiology, Duke University Medical Center
The Durham VA Medical Center, Durham, North Carolina

Correspondence: For reprints contact: Jerome M. Feldman, MD, Box 2963, Duke University Med. Ctr., Durham, NC 27710.

ABSTRACT

Iodine-131 metaiodobenzylguanidine ([¹³¹I]MIBG)is concentrated in pheochromocytomas and can be detected by external imaging. We administered [¹³¹I]MIBG to 23 patients with carcinoid tumors to determine if it would be useful in scanning patients with these tumors. The carcinoid tumors of 14 of the 23 patients (61%) were visualized. Iodine-131 MIBG was concentrated most avidly by tumors of midgut origin (ileum, cecum); it was concentrated less avidly by some tumors of foregut origin (pancreas, stomach); it was not significantly concentrated by other tumors of foregut origin (bronchus). We conclude that ¹³¹I is a useful imaging agent for carcinoid tumors.

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