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Reverse Redistribution Phenomenon in Thallium-201 Stress Tests: Angiographic Correlation and Clinical Significance

E. L. Saenger Radioisotope Laboratory
Department of Radiology and the Department of Medicine, The Jewish Hospital of Cincinnati
University of Cincinnati Medical Center, Cincinnati, Ohio

Correspondence: For reprints contact: Edward B. Silberstein, MD, Mail Location # 577, University of Cincinnati Med. Ctr., Cincinnati, OH 45267.

ABSTRACT

The reverse redistribution phenomenon (RR) with the apparent worsening of a stress-induced defect or appearance of a new area of relative hypoperfusion does not always indicate coronary artery disease as previously suggested. RR does no correlate closely with the degree of coronary artery disease, nor with the location of the stenosis. Multiple mechanisms are hypothesized wherein the "defect" may be located in the best or worst perfused area.

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