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Gallium-67 Thoracic Scan and Pleural Disease in Asbestos Workers

Département de Médecine Nucléaire et Unité de Recherche Pulmonaire, Centre Hospitalier Universitaire, Sherbrooke, Québec

Correspondence: For reprints contact: R. Bégin, MD, CHUS, Sherbrooke, Québec, J1H 5N4, Canada.

ABSTRACT

We have recently reported that ⁶⁷Ga scanning in asbestos workers can document excessive uptake of the marker among workers without sufficient criteria for asbestosis, but in our initial report we could not exclude definitely that ⁶⁷Ga uptake could be related to pleural disease. To further test this hypothesis, we analyzed the ⁶⁷Ga thoracic scan in relation to profusion scores of pleural disease on chest roentgenogram and CT scan of the thorax in 171 asbestos workers. We found no significant correlation between the ⁶⁷Ga lung uptake and the radiographic scores of pleural disease. We concluded that pleural plaques are not an active site of ⁶⁷Ga accumulation and do not contribute significantly to the thoracic uptake of the marker.