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Photon Deficient Bone Metastasis of Hepatocellular Carcinoma with Avid Gallium-67 Uptake

Nuclear Medicine Division, Medical College of Wisconsin, Milwaukee, Wisconsin

Correspondence: For reprints contact: B. David Collier, MD, Milwaukee County Medical Complex, 8700 W. Wisconsin Ave., Milwaukee, WI 53226.

ABSTRACT

While bone metastases producing photon deficient defects on bone scintigraphy have previously been reported, this finding has not been emphasized for hepatocellular carcinoma (HOC). Furthermore, "filling-in" of such photon deficient defects with ⁶⁷Ga at skeletal sites of metastatic HCC has not been described. In this case report, the combination of a photon deficient defect on bone scintigraphy and avid accumulation of ⁶⁷Ga in this same area was of value in confirming the diagnosis of metastatic HCC.