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Bone Scanning in Waldenstrom's Macroglobulinemia

Nuclear Medicine and Radiology Services, VA Medical Center, West Roxbury
Joint Program in Nuclear Medicine, Department of Radiology, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts

Correspondence: For reprints contact: Donald E. Tow, MD, Nuclear Medicine Service, VA Medical Center, 1400 VFW Parkway, West Roxbury, MA 02132.

ABSTRACT

We present a case report of a remarkably positive bone scan in a patient known to be suffering from Waldenstrom's macrogiobulinemia. Although bone involvement in this disease was originally thought not to be present, reports of bone involvement are becoming more frequent. Documenting the presence and extent of bone involvement is important because local palliative radiotherapy and/or orthopedic measures, similar to those recommended for patients suffering from multiple myeloma, may be required to prevent pathologic fractures and patient discomfort.