HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Barber, R. W. Search for Related Content PubMed PubMed Citation Articles by Barber, R. W.

Radiation Doses from Technetium-99m DTPA Administered as an Aerosol

Department of Medical Physics, Addenbrooke's Hospital, Cambridge, England

Correspondence: For reprints contact: R. W. Barber, Dept. of Medical Physics, Addenbrooke's Hospital, Cambridge, England.

ABSTRACT

A model is presented which enables radiation doses following the administration of technetium-99m diethylenetriaminepentaacetic acid ([^99mTc]DTPA) aerosol to be calculated. The organ with potential the highest radiation dose is shown to be the bladder wall. Radiation doses to the lungs, kidneys, and bladder wall and the effective whole-body dose are discussed in terms of the lung clearance rate of [^99mTc]DTPA aerosol and the pattern of bladder voiding. The model indicated the influence of urine flow rate on bladder dose assuming a critical volume at which bladder voiding occurs. It is concluded that significant reductions in radiation doses may be achieved by encouraging patients or subjects undergoing investigations using [^99mTc]DTPA aerosols to drink freely following the study.