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The University of Massachusetts Medical Center, Worcester, Massachusetts
Correspondence: For reprints contact: Michael A. King, PhD, Dept. of Nuclear Medicine, The University of Massachusetts Med. Ctr., Worcester, MA 01605.
ABSTRACT
Two-dimensional filtering, both before and after reconstruction, has been applied to the processing of single photon emission computerized tomographic (SPECT) images. The filters investigated were the count-dependent Metz filter and Wiener filter, both of which automatically adapt to the image being processed. Using a SPECT phantom, with images reconstructed with these filters rather than the ramp, we observed a statistically significant increase (p <0.05) in the image contrast for solid Plexiglas spheres, and significant decrease (p <0.05) in the percent fractional standard deviation of counts in a region of uniform activity. The adaptability of these filters is demonstrated by a comparison of SPECT acquisitions of the phantom at two different count levels. An example of their application to clinical studies is presented. We conclude that two-dimensional digital image restoration with these techniques can produce a significant increase in SPECT image quality, with a small cost in processing time when these techniques are implemented on an array processor.
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