HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Mitchell, A. Articles by Collin, J. Search for Related Content PubMed PubMed Citation Articles by Mitchell, A. Articles by Collin, J.

A Scintigraphic Method for the Assessment of Intraluminal Volume and Motility of Isolated Intestinal Segments

Oxford University, John Radcliffe Hospital, and Churchill Hospital, Oxford, England

Correspondence: For reprints contact: Dr. Andrew Mitchell, Nuffield Dept. of Surgery, Oxford University, John Radcliffe Hospital, Headington, Oxford, OX39DU, UK.

ABSTRACT

The isolated in vivo intestinal segment is a popular experimental preparation for the investigation of intestinal function, but its value has been limited because no method has been available for measuring changes in intraluminal volume under experimental conditions. We report a scintigraphic technique for measuring intraluminal volume and assessing intestinal motility. Between 30 and 180 ml, the volume of a 75-cm segment of canine jejunum, perfused with Tc-99m-labeled tin colloid, was found to be proportional to the recorded count rate. This method has been used to monitor the effects of the hormone vasopressin on intestinal function.