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An Automated Method for the Normalization of Scintigraphic Images

Service d'Exploration fonctionnelle par les Radioisotopes Hopital Cochin, Paris, France
INSERM U194, UER Pitié-Salpétrière, Paris, France

Correspondence: For reprints contact: Alain Venot, Service d'Exploration fonctionelle par les Radioisotopes, 27 rue du Faubourg St. Jacques, 75674, Paris Cedex 14, France.

ABSTRACT

The computer comparison of two images of the same organ requires normalization of the images. We propose an iterative, automated method of normalization factor is calculated by maximizing the number of sign changes in the scanned subtraction image with a unidimensional optimization method. This algorithm is efficient, computationally cheap, and can be implemented on most nuclear medicine data-processing systems.

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