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[¹³¹I] Iodocholesterol Scintiscan and a Rare "Functional" Black Adenoma of the Adrenal Cortex

University of Wisconsin, Madison, Wisconsin

Correspondence: For reprints contact: Russell M. Dixon, MD, Assistant Professor of Endocrinology, Clinical Science Ctr. H4/566, University of Wisconsin Hospital and Clinics, 600 Highland Ave., Madison, WI 53792.

ABSTRACT

A rare functional black adenoma (FBA) of the adrenal cortex was found to be the cause of hypertension and cushingoid features in a 34-yr-old white female. Preoperative studies included [¹³¹I] Iodocholesterol scanning (ICS) of the adrenal glands, which demonstrated the increased release of cortisol from the affected adrenal gland, with the failure of the opposite adrenal gland to record. This is evidence that cortisol was suppressing adrenocorticotropin (ACTH) output by the pituitary gland. This case documents the clinical utility of "functional" imaging techniques in this clinical setting.