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Diagnosis of Upper-Abdominal Infections by In-111 Labeled Leukocytes with Tc-99m Colloid Subtraction Technique

Academic Hospital, University of Amsterdam, Amsterdam, The Netherlands

Correspondence: For reprints contact: E. A. van Royen, Dept. of Nucl. Med., University Hospital, Wilhelmina Gasthuis, le Helmersstraat 104,1054 EG Amsterdam. The Netherlands.

ABSTRACT

In 65 patients suspected upper-abdominal inflammatory disease, indium-111 leukocyte scintigraphy was combined with a Tc-99m(Sn)colloid scan by computer-assisted subtraction. In 84% of these cases, a definite diagnosis would not have been possible without this method of subtraction. Accuracy was found to be 80%, sensitivity 93%, and specificity 59%. False-positive results were due either to noninfectious inflammatory lesions with accumulation of leukocytes or to some pitfalls in the subtraction technique itself.

FOOTNOTES

^* Dept. of Pediatric Surg., Sophia Kinderziekenhuis, Rotterdam, The Netherlands.