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Indium-111 Chloride Imaging in Patients with Suspected Abscesses: Concise Communication

University of Texas Medical Branch, Galveston, Texas

Correspondence: For reprints contact: Bettye A. Sayle, MD, Div. of Nucl. Med., University of Texas Medical Branch, Galveston, TX 77550.

ABSTRACT

Two hundred and fifty-eight patients with clinically suspected inflammatory processes were studied. Seventy-two images were categorized as true positive; 211 as true negative. There were nine false-positive studies, four of which were due to activity in beds of excised organs. There were six false-negative studies, four of which were due to walled-off abscesses found either at surgery or biopsy. The sensitivity was 92 %, the specificity 95 %, and the accuracy 94 %. This study shows that indium-111 chloride imaging provides a reliable way to locate inflammatory processes and overcomes the disadvantages of other imaging agents, for example gastrointestinal activity or the demonstration of healing surgical wounds with gallium-67, and the false-positive images due to cystic fibrosis and other respiratory diseases, or accessory spleens as seen with In-111-labeled white cells.