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Radioimmunoassay of Cocaine in Hair: Concise Communication

Veterans Administration Wadsworth Medical Center, University of California at Los Angeles, University of Southern California Veterans Administration Wadsworth Medical Center, University of California at Los Angeles, University of Southern California, Los Angeles, California
The Aerospace Corporation, El Segundo, California

Correspondence: For reprints contact: Werner A. Baumgartner, Ph.D., 691/115, Bldg. 500, Rm. 0068, Radioimmunoassay Laboratory, Nuclear Medicine and Ultrasound Service, Wadsworth Medical Center, Wilshire and Sawtelle Blvds., Los Angeles, CA 90073.

ABSTRACT

Cocaine was detected in hair of all of 13 patients from a drug-abuse clinic who acknowledged having used the drug in varying amounts during the last 6 mo. A correlation was observed between the amount of drug used and the quantity trapped in the interior of hair grown during the 6-mo period. In contrast to hair analysis, urinalysis by thin-layer chromatography was negative in all cases, indicating that cocaine had not been used by the patients within 48–72 hr before the urine collection. Hair analysis thus appears to be far superior to urinalysis for establishing histories of drug use.

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