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Necropsy of a Cadaver Containing 50 mCi of Sodium¹³¹Iodide

Roswell Park Memorial Institute, New York State Department of Health, and the State University of New York at Buffalo, Buffalo, New York

Correspondence: For reprints contact: K. L. Parthasarathy, MD, Dept. of Nuclear Medicine, Roswell Park Memorial Institute, 666 Elm St., Buffalo, NY 14263.

ABSTRACT

A patient who received an oral dose of iodine-131 for the treatment of metastatic thyroid carcinoma unexpectedly died with a large total-body retention of the radioiodine. An autopsy was required and the family requested the body to be transported out of state to their home town. Since the radiation intensity near the surface of the cadaver was above 200 mR/hr, advanced planning and special precautions were necessary in order for the autopsy to proceed safely. This required the immediate cooperation of the pathologists, nuclear medicine physicians, health physicists, an endocrine oncologist, and other hospital staff. As a result of team efforts, personnel radiation exposures were kept as low as reasonably achievable, contamination of the autopsy room was minimal, and the radiation level of the cadaver was adequately reduced for safe transport and burial.