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Donor-Leukocyte Imaging in Granulocytopenic Patients with Suspected Abscesses: Concise Communication

University of Utah College of Medicine, Salt Lake City, Utah

Correspondence: For reprints contact: R. E. Coleman, MD, Box 3949, Dept. of Radiology, Duke Univ. Med. Ctr., Durham, NC 27710.

ABSTRACT

Indium-111-labeled donor leukocytes were used for the detection of foci of suppuration in eight severely leukopenic patients with marrow suppression, either idiopathic or associated with chemotherapeutic regimens for leukemia. In three patients good correlation was found between the results of imaging and clinical signs or subsequent proof of inflammation. In the other five patients, in whom no evidence of localized suppuration occurred, no abnormal accumulations of radioactivity were demonstrable. Labeled donor leukocytes provide a method for locating suppurative foci in severely leukopenic patients in whom autologous leukocyte labeling is impractical.

FOOTNOTES

^* Present address: Dept. of Radiology, Duke Univ. Med. Ctr., Durham, NC 27710.

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