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Technetium-99m DTPA Splenic Uptake

William Beaumont Hospital, Royal Oak, Michigan

Correspondence: For reprints contact: Darlene Fink-Bennett, Nuclear Medicine Dept., William Beaumont Hospital, 3601 West 13 Mile Rd., Royal Oak, MI 48072.

ABSTRACT

Splenic uptake of technetium-99m DTPA was observed during the performance of a diuresis renogram in a 52-year-old male with an active infection of the upper urinary tract.The exact mechanism of uptake is uncertain, but we postulate that it is secondary to a contiguous splenic inflammatory process with its concomitant increase in capillary permeability and breakdown of blood/tissue barriers.