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Scintigraphic Detection of Intrapulmonary Bleeding Using Technetium-99m Sulfur Colloid: Concise Communication

Veterans Administration Medical Center, San Diego, California
University of California, San Diego, California

Correspondence: For reprints contact: Naomi P. Alazraki, MD, 500 Foothill Dr., VA Medical Ctr., Salt Lake City, UT 84148.

ABSTRACT

Radionuclide imaging has been successfully used clinically to determine sites of gastrointestinal hemorrhage, but its use in hemoptysis has not been studied. A dog model of intrapulmonary hemorrhage was devised. Utilizing technetium sulfur colloid, at doses of 4 and 15 mCi, bleeding rates of 0.1–0.2 cc/min were detected. in some dogs, however, significantly higher bleeding rates were not detected. The largest source of error arose from bleeding into a large bronchus, which causes a diffuse distribution of the radionuclide.