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Simultaneous Display of Gated Technetium-99m Stannous Pyrophosphate and Gated Blood-Pool Scintigrams

University of Texas Health Science Center and Parkland Memorial Hospital, Dallas, Texas

Correspondence: For reprints contact: James R. Corbett, MD. Ischemie Heart Center, Room L5.134, The University of Texas Health Science Center at Dallas, 5323 Harry Hines Blvd., Dallas, TX 75235.

ABSTRACT

We have developed a method by which any two sets of R-wave-synchronized radionuclide images may be registered, color-coded, and displayed in cinematic fashion so that the image sets are superimposed and shown simultaneously in contrasting colors. The technique has been applied to technetium-99m stannous pyrophosphate (Tc-99m PPi) and equilibrium blood-pool images. Gated Tc-99m PPi and gated blood-pool image sets (16 frames per cardiac cycle) were acquired in identical projections. Image sets were then registered, if necessary, and color-coded by a computer algorithm. Our initial experience suggests that this overlay technique may be of value to: (a) detect right ventricular infarction with greater precision; (b) provide a better estimate of anatomic location and circumferential extent of Tc-99m PPi myocardial uptake relative to the ventricular blood pool; and (c) distinguish between segmental contraction abnormalities caused by recent infarction (identified by abnormal Tc-99m PPi uptake) and segmental contraction abnormalities caused by ischemia or previous myocardial infarction.