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Pulmonary Scintigraphy in Fibrosing Mediastinitis Due to Histoplasmosis

Indiana University School of Medicine and Methodist Hospital Graduate Medical Center, Indianapolis, Indiana

Correspondence: For reprints contact: H. Park, MD, Chief, Nuclear Medicine, Wishard Memorial Hospital, Indianapolis, IN 46202.

ABSTRACT

The pulmonary scintigraphic findings from four patients with fibrosing mediastinitis due to histoplasmosis are reported. The ventilation/perfusion (V/Q) mismatch mimicked pulmonary emboli. However, in these cases the chest radiographs and/or gallium-67 scintigraphy were abnormal, suggesting mediastinal or hilar disease. Awareness of the nonembolic conditions that can result in V/Q mismatches is important in the interpretation of lung scans.