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Tc-99m Pyrophosphate Myocardial Scanning in Chagas' Disease

Hospital Beneficencia Portuguesa, Rio de Janeiro, Brazil
Georgetown University Hospital, Washington, D.C.

Correspondence: For reprints contact: John C. Harbert, MD, Div. of Nuclear Medicine, Georgetown University Hospital, Washington, D.C. 20007.

ABSTRACT

Chagas' disease is a serious protozoan infection affecting up to 20% of populations in some endemic areas. Myocarditis and cardiomyopathy occur in 50% of patients who go on to develop chronic Chagas' disease. We have studied a patient with no overt cardiac symptoms who revealed intense myocardial uptake of Tc-99m pyrophosphate. The significance of this finding in relation to early detection and progress of therapy is explored.