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The Journal of Nuclear Medicine Vol. 22 No. 12 1081-1083
© 1981 by Society of Nuclear Medicine
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Decreased Accumulation of Isopropyl-Iodoamphetamine (I-123) in Brain Tumors

Norman D. LaFrance, Henry N. Wagner, Jr., Peter Whitehouse, Edward Corley and Timothy Duelfer

The Johns Hopkins Medical Institutions, Baltimore, Maryland

Correspondence: For reprints contact: Norman D. LaFrance, MD, Nuclear Medicine, John Hopkins Medical Institutions, 615 N. Wolfe Street, Baltimore, MD 21205.

ABSTRACT

Four out of four patients with brain tumors were observed to have impaired N-isopropyl-p-[123I]iodoamphetamine (IAMPH) accumulation by the lesions even though brain scans with technetium-99m diethylenetriamine pentaacetic acid were normal in two. IAMPH may be a more sensitive means of detecting regional cerebral disease than tracers primarily sensitive to blood-flow abnormalities or impairment of the blood-brain barrier.




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Y. Akiyama, K. Moritake, T. Yamasaki, Y. Kimura, A. Kaneko, Y. Yamamoto, T. Miyazaki, and M. Daisu
The Diagnostic Value of 123I-IMP SPECT in Non-Hodgkin's Lymphoma of the Central Nervous System
J. Nucl. Med., November 1, 2000; 41(11): 1777 - 1783.
[Abstract] [Full Text] [PDF]




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Copyright © 1981 by the Society of Nuclear Medicine.