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Posture-Induced Disturbance of Pertechnetate Flow and I-123 Iodohippurate Transport in Some Renal Graft Recipients with Hypertension

German Cancer Research Center, the University of Heidelberg, and the Stiftung Rehabilitation, Heidelberg, Germany

Correspondence: For reprints contact: John H. Clorius, MD, Institute of Nuclear Medicine, German Cancer Research Ctr., P.O. Box 109149, D-6900 Heidelberg 1, Germany.

ABSTRACT

Iodohippurate renography and rapid serial scintigrams with pertechnetate were done in 27 allograft recipients in supine and standing positions. Posture-dependent iodohippurate transport and/or disturbance of pertechnetate flow pattern was found in nine of those examined. Patients demonstrating these abnormalities were found to be hypertensive. We suggest a causal relationship between posttransplant hypertension and the described posture-induced alterations of tracer transit.