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The Journal of Nuclear Medicine Vol. 21 No. 2 126-129
© 1980 by Society of Nuclear Medicine
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Comparison of Four Commercial Tc-99m(Sn)DTPA Preparations Used for the Measurement of Glomerular Filtration Rate: Concise Communication

Jan E. Carlsen, Michael Lehd Møller, Jens O. Lund and Jens Trap-Jensen

Frederiksberg Hospital, DK—2000 Copenhagen F, Denmark

Correspondence: For reprints contact: Jan E. Carlsen, Dept. of Clinical Physiology, Frederiksberg Hospital, DK-2000 Copenhagen F, Denmark.

ABSTRACT

To find a commercially available DTPA preparation that could be used for the measurement of glomerular filtration rate (GFR), the plasma clearances of four different Tc-99m(Sn)DTPA preparations were compared with that of Cr-51 EDTA using a single-injection technique. One preparation yielded results identical to those obtained with Cr-51 EDTA, whereas the others underestimated the GFR to a varying degree. It is concluded that Tc-99m DTPA can be used to estimate the GFR, but that the accuracy will depend on the commercial source.




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Copyright © 1980 by the Society of Nuclear Medicine.