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Patterns of Ventricular Emptying by Fourier Analysis of Gated Blood-Pool Studies

Johns Hopkins Medical Institutions, Baltimore, Maryland

Correspondence: For reprints contact: Jonathan M. Links, The Johns Hopkins Medical Institutions, Div. of Nuclear Medicine and Radiation Health Sciences, 615 N. Wolfe St., Baltimore, MD 21205.

ABSTRACT

Temporal Fourier analysis was applied to the processing of ECG-gated cardiac blood-pool studies on a pixel-by-pixel basis, to yield information about the pattern of ventricular emptying in normal hearts and in others with conduction abnormalities. The transform data at the fundamental frequency (the heart rate) were used to construct two types of display: (a) a distribution histogram of the pixel phase values, and (b) a cinematic display of the wave of emptying as it spread over the cardiac chambers. Preliminary results indicate that temporal Fourier analysis permits visualization of the pattern of ventricular emptying, which may prove useful in the study of motion abnormalities and asynergies, including those resulting from myocardial hypertrophy or conduction abnormalities, and as an aid in the optimum placement of pacemakers.

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