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The Journal of Nuclear Medicine Vol. 21 No. 1 59-62
© 1980 by Society of Nuclear Medicine
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Improved Protein Labeling By Stannous Tartrate Reduction of Pertechnetate

William A. Pettit, Frank H. DeLand, Sidney J. Bennett and David M. Goldenberg

Veteran's Administation Medical Center and University of Kentucky Medical Center, Lexington, Kentucky

Correspondence: For reprints contact: William A. Pettit, Nuclear Medicine Service, Veterans Administration Medical Center, Lexington, KY 40507.

ABSTRACT

A procedure has been developed whereby small amounts of protein—specifically human serum albumin and immunoglobulin G—can be labeled with Tc-99m. Artifactual problems associated with electrolytic and stannous chloride labeling procedures are virtually eliminated. The procedure is satisfactory for labeling human serum albumin, normal goat immunoglobulin G, and goat anti-carcinoem-bryonic antigen immunoglobulin G.






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Copyright © 1980 by the Society of Nuclear Medicine.