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Effect of Food Intake on the Tissue Distribution of Gallium-67: Concise Communication

Oak Ridge Associated Universities, Oak Ridge, Tennessee

Correspondence: For reprints contact: Raymond L. Hayes, Oak Ridge Associated Universities, P. O. Box 117, Oak Ridge, TN 37830.

ABSTRACT

Fasting affects the body retention and tissue distribution of Ga-67 in experimental animals. In Ga-67 experiments, therefore, a difference in food intake between treated and control animals might result in confusing side effects. We have observed this in irradiation studies. It is suggested that a fasting regimen should be imposed in any Ga-67 animal study where an alteration in food intake might be experienced in the treated group.

FOOTNOTES

^* Poland-U.S. (NCI) Exchange Scientist from Maria Sklodowska-Curie Memorial Institute of Oncology, Warsaw 22, Poland.