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The Journal of Nuclear Medicine Vol. 20 No. 7 785-788
© 1979 by Society of Nuclear Medicine
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Radioiodinated DNA as Potential Tumor-Imaging Agent

Dionyssis S. Ithakissios and Bern Hapke

3M Company, St. Paul, Minnesota

Correspondence: For reprints contact: Bern Hapke, Medical Products Dept., Bldg 230-3, 3M Company, St. Paul, MN 55101.

ABSTRACT

Radiolabeled heat-denatured DNA and some related nucleic acids localize in tumor tissue following i.v. administration. Retention of radioactivity by tumors is longer than for other organs and localization of tumor tissues is possible by scintigraphic techniques 8–24 hr after injection.






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Copyright © 1979 by the Society of Nuclear Medicine.