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The Journal of Nuclear Medicine Vol. 20 No. 7 771-777
© 1979 by Society of Nuclear Medicine
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"Circumferential Profiles:" A New Method for Computer Analysis of Thallium-201 Myocardial Perfusion Images

Robert D. Burow, Malcolm Pond, A. William Schafer and Lewis Becker

The Johns Hopkins University School of Medicine, Baltimore, Maryland

Correspondence: For reprints contact: Lewis Becker, The Johns Hopkins Hospital, Cardiology Div., 600 N. Wolfe St., Baltimore, MD 21205.

ABSTRACT

A method for computer analysis of thallium-201 scintigrams is described, in which the left-ventricular activity is measured along radii constructed from the center of the left ventricle (LV) to each point on the LV circumference. Data are then displayed graphically as a \ldcircumferential profile\rd of normalized activity against radial location. Thallium defects are identified and scored by comparison of the profile curve with empirically determined normal limits. In patients with coronary artery disease, defect scores were found to be quantitative and reproducible, and to agree generally with subjective visual analysis.




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