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Brain and Lung Involvement of Mycosis Fungoides Demonstrated by Radionuclide Imaging

Veterans Administration Hospital University of Kentucky Medical Center, Lexington, Kentucky

Correspondence: For reprints request: E. Kim, Div. of Nuclear Medicine, University of Kentucky Medical Center, 800 Rose St., Lexington, KY 40506.

ABSTRACT

A patient with advanced mycosis fungoides developed neurologic and respiratory symptoms and signs following multiple courses of chemotherapy and radiotherapy. Various repeated diagnostic procedures—including cranial computerized tomography and fiberoptic bronchoscopy with transbronchial lung biopsy—failed to demonstrate an unusual involvement of the brain and lungs by mycosis fungoides. Radionuclide brain imaging and gallium imaging of the lungs demonstrated diffuse lesions confirmed at autopsy.