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Localization of Ga-67 in Inflammations in the Absence of Circulating Polymorphonuclear Leukocytes

University of Connecticut Health Center, Farmington, Connecticut
Hartford Hospital, Hartford, Connecticut

Correspondence: For reprints contact: Richard P. Spencer, Dept. of Nuclear Medicine, University of Connecticut Health Ctr., Farmington, CT 06032.

ABSTRACT

Two cases are reported in whom there were no circulating polymorphonuclear leukocytes, on peripheral blood smears, at the time when Ga-67 citrate studies were carried out. In both of these women, Ga-67 accumulated at sites of inflammation. This shows that nonpolymorphonuclear pathways are sufficient to deliver Ga-67 and to allow its accumulation. The possible roles of lymphocytes or of noncellular pathways (such as transferrin to tissue lactoferrin) are mentioned.