HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Taylor, A. Articles by Talner, L. B. Search for Related Content PubMed PubMed Citation Articles by Taylor, A. Articles by Talner, L. B.

Relative Renal Accumulation of Tc-99m Penicillamine as an Index of Differential Renal Function: Concise Communication

Veterans Administration Hospital and the University of California School of Medicine, San Diego, California

Correspondence: For reprints contact: Andrew Taylor, Jr., Nuclear Medicine Service (115), Veterans Administration Hospital, 3350 La Jolla Village Dr., San Diego, CA 92161.

ABSTRACT

The relative renal accumulation of technetium-99m penicillamine (TPEN) was evaluated as an index of differential renal function. Using a scintillation camera interfaced to a computer, renal uptake of TPEN was determined for each kidney by subtracting the renal activity at 10 min from that at 25 min. This percentage of TPEN activity in the left kidney was compared with the percentage of total creatinine clearance contributed by the left kidney in six patients with ureteral obstruction and nephrostomy drainage. The two measurements agreed extremely well, with a correlation coefficient of 0.98. The relative renal uptake of TPEN and similar cortex imaging agents such as Tc-99m dimercaptosuccinic acid can probably be used to assess differential renal function.