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Collimation for Imaging the Myocardium. II

University of California at Los Angeles and Laboratory of Nuclear Medicine and Radiation Biology, Los Angeles, California

Correspondence: For reprints contact: L. Stephen Graham, Nuclear Medicine Div., AR-144B, Center for the Health Sciences, University of California, Los Angeles, CA 90024.

ABSTRACT

Line-source response functions and modulation transfer functions (MTF) were used to compare the spatial resolutions obtained with an Anger camera system and four different nuclides used as myocardial-imaging agents: ^99mTc, ¹²³I, ²⁰¹Tl, and ⁴³K. The measurements were made with a low-energy converging collimator (LEC), a medium-energy converging collimator (MEC), and a pinhole collimator. The MTF values for ^99mTc were very similar for all three collimator types, although the LEC collimator gave slightly higher values at high spatial frequencies and had 40% greater sensitivity. Iodine-123 was satisfactorily imaged only with the MEC and pinhole collimators, which in turn yielded MTF values comparable to those measured for ^99mTc Thallium-201 produced MTF curves that were similar for the MEC and pinhole collimators; the curve for the LEC collimator was slightly poorer. All three MTF curves for ²⁰¹Tl were inferior to those of ^99mTc. For imaging with ⁴³K, only the pinhole collimator provided marginally acceptable spatial resolution.