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The Journal of Nuclear Medicine Vol. 17 No. 10 930-936
© 1976 by Society of Nuclear Medicine
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A New Dual-Probe System for the Rapid Bedside Assessment of Left Ventricular Function

Mark W. Groch, Stuart Gottlieb, Stephen M. Mallon and August Miale, Jr.

University of Miami School of Medicine, Jackson Memorial Hospital, Miami, Florida
Searle Radiographics, Inc., Des Plaines, Illinois

Correspondence: For reprints contact: M. W. Groch, Research Dept., Searle Radiographics, Inc., 2000 Nuclear Drive, Des Plaines, IL 60018.

ABSTRACT

A mobile dual-probe system has been developed for the rapid bedside measurement of left ventricular ejection fraction (LVEF) from the beat-to-beat count rate variations that occur during the transit of a single radionuclide bolus through the left ventricle (LV). Cardiac output, pulmonary blood volume, and left ventricular end-diastolic volume can also be calculated. The dual-probe system incorporates a central collimated probe for monitoring activity in the LV surrounded by an annular detector collimated in such a manner as to provide simultaneous real-time monitoring of the LV background activity. The LVEFs obtained from this system correlated well with LVEFs derived from conventional single-plane contrast angiography (r = 0.90) in a series of 33 patients with coronary artery disease. Positioning the dual probe over the midpoint of the LV is accomplished with standard M-mode ultrasound. Since the method is noninvasive and sensitive to volume changes in the LV, the dual probe is particularly useful for monitoring seriously ill patients as well as those wilh segmental wall-motion abnormalities.






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Copyright © 1976 by the Society of Nuclear Medicine.