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Renal Localization of ⁶⁷Ga-Citrate in Renal Amyloidosis: Case Reports

University of Chicago, Chicago, Illinois

Correspondence: For reprints contact: Carlos Bekerman, Div. of Nuclear Medicine, Michael Reese Medical Center, Chicago, IL 60616.

ABSTRACT

In scans taken 72 hr after intravenous administration of 5 mCi of ⁶⁷Ga-citrate, both kidneys were clearly visible in two cases of histologically proven renal amyloidosis. Neither patient had clinical manifestations or laboratory evidence of concurrent inflammatory disease or tumor involving the kidneys. Increased renal concentration of lysosomal organelles and increased affinity of ⁶⁷Ga for amyloid material contained in the organelles could explain the renal uptake of ⁶⁷Ga in amyloidosis.