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The Journal of Nuclear Medicine Vol. 16 No. 9 839-841
© 1975 by Society of Nuclear Medicine
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Cobalt-Labeled Bleomycin—A New Radiopharmaceutical for Tumor Localization. A Comparative Clinical Evaluation with Gallium Citrate

Kattadiyil P. Poulose, Anthony E. Watkins, Richard C. Reba, William C. Eckelman and Margaret Goodyear

Washington Hospital Center and George Washington University, Washington, D.C.

Correspondence: For reprints contact: William C. Eckelman, Division of Nuclear Medicine, George Washington University Hospital, Washington, D.C. 20037.

ABSTRACT

The efficacy of 57Co-labeled bleomycin as a tumor-scanning agent was evaluated in 50 patients with malignant tumor. In terms of sensitivity, labeled bleomycin was found to be a superior agent for malignant tumor detection when compared with 67Ga-citrate (p ≤ 0.005). Maximum sensitivity (96%) was found in epidermoid carcinomas. Because of rapid blood clearance and rapid excretion by the kidneys, interpretation of 57Co-bleomycin scans is facilitated.







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Copyright © 1975 by the Society of Nuclear Medicine.