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Bone Marrow Imaging Using ¹¹¹In-Citrate: ¹¹¹In-Kinetics in the Pelvic Region

Institut für Nuklearmedizin and Medizinische Klinik, Städtische Krankenanstalten, Krefeld, West Germany

Correspondence: For reprints contact: Dieter M. H. Glaubitt, Institut für Nuklearmedizin, Städtische Krankenanstalten Krefeld, D-415 Krefeld, West Germany.

ABSTRACT

When bone marrow scintigraphy was performed using ¹¹¹In-citrate, radioactivity was observed in the pudendal region. Subsequently, the kinetics of ¹¹¹In the pelvic region after intravenous administration of ¹¹¹In-citrate for bone-marrow scanning in 14 patients was examined. On the first day, radioindium was found predominantly in the large pelvic blood vessels and in the pudendal region. In all male patients, the scrotal area was affected with both testes presumably delineated in two patients. In the female patients little radioindium was detected in the pudendal region, most probably in the vulva; distinct radioactivity was found in the pelvis although the ovaries could not be identified. In the following period the ¹¹¹In uptake in the bone marrow increased considerably and reached its maximum usually 24 hr after the injection. Because a distinct radiation dose from ¹¹¹In to the gonads cannot be excluded on the basis of our scintigraphic findings and the absorbed dose has not yet been estimated sufficiently, judgment should be used for the present if ¹¹¹In-citrate is applied for bone marrow imaging.