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Kyushu University, Fukuoka
Daiichi Radioisotope Laboratories, Ltd., Tokyo, Japan
Correspondence: For reprints contact: Masaharu Kojima, Faculty of Pharmaceutical Sciences, Kyushu University, Maedashi 3-chome 1-1, Higashi-ku, Fukuoka 812, Japan.
ABSTRACT
A new adrenal-specific compound, 6ß-iodomethyl-19-norcholest-5(10)-en-3ß-ol (NCL-6-I), which is derived from 19-iodocholesterol (CL-19-I), has been found. Tissue distribution studies have revealed that the rat adrenal gland accumulates ten times more NCL-6-131I than CL-19-131I. The advantage of NCL-6-131I as a possible adrenal-scanning agent is discussed.
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