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Iodine-123-Rose Bengal: An Improved Hepatobiliary Imaging Agent

University of Miami School of Medicine, Mount Sinai Medical Center, Miami Beach, Florida

Correspondence: For reprints contact: Aldo N. Serafini, Div. of Nuclear Medicine, University of Miami School of Medicine, Mount Sinai Medical Center, Miami Beach, Fla. 33140.

ABSTRACT

A practical method for preparing ¹²³I-rose bengal that allows for its rapid and efficient incorporation into the molecule is reported. Administration of ¹²³I-rose bengal to normal healthy patients showing the normal uptake and excretory pattern visualized with this radiopharmaceutical is also presented. The overall reduction in imaging time and radiation exposure together with the improved images possible should greatly improve our diagnostic capabilities in evaluating the jaundiced patient.