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Loculation as a Contraindication to Intracavitary ³²P-Chromic Phosphate Therapy

University of California, San Diego
School of Medicine, La Jolla, California

Correspondence: For reprints contact: Andrew Taylor, Dept. of Nuclear Medicine (172), 3350 La Jolla Village Dr., San Diego, Calif. 92161.

ABSTRACT

Loculation of instilled ^99mTc-sulfur colloid solution in the peritoneal cavity was observed in a patient being considered for intracavitary therapy with ³²P-chromic phosphate. Since intracavitary instillation of a therapeutic dose of a radiopharmaceutical agent into a loculated space would risk therapeutic failure and tissue necrosis, prior instillation of a tracer nuclide is recommended to insure adequate dispersion before beginning such therapy.