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Evaluation of Portable Radionuclide Method for Measurement of Left Ventricular Ejection Fraction and Cardiac Output

Theodore Berndt^*, Edwin L. Alderman, Richard Wasnich, San C. Hsieh, Donald Van Dyke^|| and Donald C. Harrison

Stanford University School of Medicine, Stanford, California

Correspondence: For reprints contact: Edwin L. Alderman, Cardiology Div., Stanford University Medical Center, Stanford, Calif. 94305.

ABSTRACT

Seventeen patients with coronary artery, valvular, or myopathic heart disease were studied to determine correlations of the cardiac output and ejection fraction when comparing the results obtained with a portable probe technique using ^113mIn with those obtained with standard methods (cineangiographic, Fick, and dye dilution). With ejection fractions ranging from 0.10 to 0.85, the coefficient of correlation was 0.90 when comparing cineangiographic and radionuclide techniques. Cardiac output determinations by the radionuclide technique also correlated well with standard methods (r = 0.88). The radionuclide method shows promise as an accurate, safe, and simple method in the evaluation of cardiac function at the bedside.

FOOTNOTES

^* Present addresses: West Jefferson Hospital, 908 Christana Place, Gretna, La. 70053.

Kuakini Hospital, 347 N. Kuakini, Honolulu, Hawaii 96817.

2161 Garnet Ave., San Diego, Calif. 92109.

^|| Donner Laboratory, University of California, Berkeley, Calif. 94720.