HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Cummings, D. M. Articles by Wagner, H. N. Search for Related Content PubMed PubMed Citation Articles by Cummings, D. M. Articles by Wagner, H. N., Jr.

Radiometric Detection of the Metabolic Activity of Mycobacterium Tuberculosis

National Health Laboratory, Arlington, Virginia
First Army Medical Laboratory, Fort Meade, Maryland
Johns Hopkins Medical Institutions, Baltimore, Maryland

Correspondence: For reprints contact: Henry N. Wagner, Jr., 615 N. Wolfe Street, Baltimore, Md. 21205.

ABSTRACT

A radiometric test capable of detecting the metabolic rate of M. tuberculosis within 18 hr after inoculation has been developed. The technique is based on the measurement of ¹⁴CO₂ produced by the bacterial metabolism of ¹⁴C-U-glycerol or ¹⁴C-U-acetate. The test is an important first step in the development of rapid radiometric techniques for clinical study of Mycobacterium tuberculosis.